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Michael P Barrett Selected Research

Pentamidine (NebuPent)

1/2019Genomic instability at the locus of sterol C24-methyltransferase promotes amphotericin B resistance in Leishmania parasites.
12/2010Potential new drugs for human African trypanosomiasis: some progress at last.
8/2010Diamidines for human African trypanosomiasis.
1/2006Targeting of toxic compounds to the trypanosome's interior.
5/2003Pentamidine uptake and resistance in pathogenic protozoa: past, present and future.

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Michael P Barrett Research Topics

Disease

30African Trypanosomiasis (Nagana)
01/2021 - 01/2002
9Leishmaniasis
01/2021 - 11/2005
8Malaria
12/2021 - 02/2002
7Infections
01/2021 - 05/2009
5Trypanosomiasis
01/2021 - 11/2005
5Chagas Disease (American Trypanosomiasis)
02/2020 - 01/2002
4Neglected Diseases
02/2020 - 11/2003
2Visceral Leishmaniasis (Kala Azar)
12/2017 - 01/2012
1Prostatic Neoplasms (Prostate Cancer)
01/2021
1Rheumatoid Arthritis
06/2020
1Hypoxia (Hypoxemia)
01/2020
1Sepsis (Septicemia)
01/2020
1Persistent Infection
10/2019
1Genomic Instability
01/2019
1Hypersensitivity (Allergy)
01/2019
1Sleepiness
12/2016
1Neoplasms (Cancer)
07/2013
1Parasitemia
01/2013
1Inflammation (Inflammations)
05/2009
1Brain Diseases (Brain Disorder)
05/2009
1Body Weight (Weight, Body)
10/2003
1DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes)
10/2003
1Communicable Diseases (Infectious Diseases)
05/2003
1Falciparum Malaria (Plasmodium falciparum Malaria)
02/2002

Drug/Important Bio-Agent (IBA)

25Pharmaceutical PreparationsIBA
12/2021 - 01/2002
5Amphotericin B (Amphotericin)FDA LinkGeneric
01/2019 - 11/2005
5Pentamidine (NebuPent)FDA LinkGeneric
01/2019 - 05/2003
4Glucose (Dextrose)FDA LinkGeneric
01/2021 - 02/2004
4fexinidazoleIBA
02/2020 - 06/2011
4Eflornithine (Ornidyl)FDA Link
01/2015 - 11/2005
4Melarsoprol (Mel B)IBA
09/2011 - 01/2002
4Phosphogluconate Dehydrogenase (Dehydrogenase, Phosphogluconate)IBA
08/2010 - 07/2003
3Biomarkers (Surrogate Marker)IBA
01/2021 - 12/2016
3Biological ProductsIBA
01/2019 - 07/2003
3NifurtimoxIBA
01/2012 - 01/2002
2UbiquitinIBA
12/2021 - 01/2020
2artemisinin (artemisinine)IBA
12/2021 - 01/2020
2ArtemisininsIBA
12/2021 - 01/2020
2Antimalarials (Antimalarial Agents)IBA
12/2021 - 01/2021
2miltefosine (Impavido)IBA
01/2018 - 11/2005
2TriazolesIBA
12/2017 - 01/2012
2liposomal amphotericin BFDA Link
12/2017 - 01/2012
2AntigensIBA
01/2016 - 02/2002
2benzonidazole (benznidazole)IBA
05/2014 - 01/2012
2PolyaminesIBA
01/2012 - 08/2003
2PurinesIBA
08/2010 - 08/2005
2EnzymesIBA
07/2010 - 08/2007
1Antiparasitic Agents (Antiparasitics)IBA
12/2021
1Antineoplastic Agents (Antineoplastics)IBA
12/2021
1Deubiquitinating EnzymesIBA
12/2021
1Proteasome Endopeptidase Complex (Proteasome)IBA
12/2021
1Clemastine (Clemastine Fumarate)FDA LinkGeneric
01/2021
1Meglumine AntimoniateIBA
01/2021
1Proline (L-Proline)FDA Link
01/2021
1Trypanocidal AgentsIBA
01/2021
1Suramin (Suramin Sodium)IBA
12/2020
1Amino AcidsFDA Link
12/2020
1itaconic acidIBA
06/2020
1Antirheumatic Agents (DMARD)IBA
06/2020
1Proteasome InhibitorsIBA
02/2020
1Lactic Acid (Lactate)FDA LinkGeneric
01/2020
1HydrolasesIBA
01/2020
1Carnitine (L-Carnitine)FDA LinkGeneric
01/2020
1SterolsIBA
01/2019
1ER 30346 (ravuconazole)IBA
12/2017
1Serotonin (5 Hydroxytryptamine)IBA
12/2016
15-Hydroxytryptophan (5 Hydroxytryptophan)IBA
12/2016
1PyrimidinesIBA
06/2015
1IsotopesIBA
03/2015
1ArginaseIBA
10/2013
1DiminazeneIBA
01/2013
1CTP synthetaseIBA
09/2012
1CyclodextrinsIBA
09/2011
1NitroimidazolesIBA
06/2011
13-bromoacivicinIBA
02/2011
1NucleosidesIBA
08/2010
1Ro 61-8048IBA
05/2009
1KynurenineIBA
05/2009
1benzamidineIBA
10/2008
1Guanidine (Guanidine Nitrate)FDA Link
10/2008
1Phosphates (Orthophosphate)IBA
08/2007
1PentosesIBA
08/2007
1pafuramidineIBA
11/2006
1amidoximeIBA
11/2006
1ProdrugsIBA
11/2006
1furamidine (DB75)IBA
11/2006
1melamineIBA
01/2006
1Paromomycin (Paromomycin Sulfate)FDA LinkGeneric
11/2005
1diminazene aceturateIBA
05/2004
1Proteins (Proteins, Gene)FDA Link
01/2004
1ThiadiazolesIBA
10/2003
1megazolIBA
10/2003

Therapy/Procedure

9Therapeutics
06/2020 - 09/2008
4Drug Therapy (Chemotherapy)
12/2016 - 01/2002
1Aftercare (After-Treatment)
01/2013
1Combination Drug Therapy (Combination Chemotherapy)
05/2009